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![]() ![]() But most importantly, after helping care for my grandmother during her illness and being at her side for her last breath, no one will have to twist my arm about getting my first colonoscopy during this, my 50 th year. I’ve also decided to give up social drinking, except for the occasional glass of red wine. Once my sons are out of the house I plan to commit to a vegetarian diet, like my daughter, because I side with the research that shows vegetarians tend to be on lowest rung of the cancer-risk ladder. I, for one, have become cautious about what I eat and avoid red meat. Needless to say my family members and I grew concerned about a genetic predisposition to the disease. But we don’t just rely on history to prove the therapeutic benefit of… MORE ⟩⟩ That explains why it was documented in the oldest medical writings. The golden-colored oil of the Nigella sativa plant contains compounds essential for a healthy immune system. Another of my grandmother’s nieces was diagnosed early and has, thankfully, been cancer free for several years. But rather than a trick, fate may have been more like it.īefore my family suffered the devastating loss of our beloved matriarch, my grandmother lost her baby sister and another sister’s daughter to the same dreaded disease a few years earlier. ![]() To live such a long healthy life only to be forced to battle such a formidable enemy in her golden years seemed like a cruel trick of fate. I was very angry when she was diagnosed about a year before we lost her. I recently lost my grandmother at the age of 88 to colon cancer. But she and her sisters were never really far from each other, visited often and remained close throughout the years. My grandmother left her small hometown to marry my grandfather–a dark-haired handsome Italian gentleman who whisked her away to a bigger city a state over. My grandmother was the most loving person I’ve encountered in life, and one of five beautiful southern sisters who grew up in Aberdeen, Mississippi. ![]() ![]() You can continue to Choose Files or Close the Uploader window if completeġ. Choose Files to Upload: Select this option to open File Explorer, navigate to file(s) you wish to upload, select one ore more file(s), then select Open to begin the uploadĤ. Drag & Drop: Select one or more file(s) from a location on your PC (using File Explorer or from Desktop, etc) then drag & drop them into the area indicated in the web browser's Upload Content areaī. Add files by Drag & Drop or Choose Files to Upload:Ī. If no content exists, you can also select the "Use the uploader to add some content." hyperlinkĤ. Select the Upload icon at top of the library folder page. Type in name for new library folder then press ENTERģ. Select the "+" to the right of Folders in the left-hand paneī. Select or create the Library folder to which you want to upload SWF video file(s)Ī. Login to with your TechSmith or Screencast login (you can create one for free on this site, if you don't have one already)Ģ. To upload Jing (SWF) or other media files to Screencast:ġ. You can also manage your content within Screencast.Ī full step-by-step help guide to using Screencast can be found at: When you wish to view or share them, you will need to upload to Screencast, then View or Share from there. Old "Jing" (".SWF" aka Adobe Flash) files can still be stored within your OneDrive or other location (Teams, Sharepoint, local hard drive, etc). Storage of content limited to 12 months. ![]() There are limitations to a FREE Screencast account: Using Screencast, you can upload, view and share SWF (Jing), MP4 (Capture) and many other video formats. Capture also only provides option to "Save" videos by uploading to Screencast. Since SWF format is discontinued with Capture, you will no longer be able to view the video (SWF) files from Jing using the TechSmith application. Jing only supported saving video files in SWF (Adobe Flash) file format. Screencast: How to View "Jing" Video Files & Manage Content
![]() ![]() Information for these orders is for review only. When set to Disabled, your Amazon orders will display in the Orders tab but will not have a corresponding Magento order number and cannot be managed in Amazon Sales Channel. Must be set to Enabled to manage Amazon orders in Amazon Sales Channel. Magento orders are created based on Amazon status and stock levels. ![]() When this option is selected, all other fields on this screen are disabled.Įnabled: Choose when you want to create corresponding Magento orders when new orders are received from Amazon. Creates the Magento order To configure Order Settings:Ĭlick Order Settings in the onboarding progress bar.įor Import Amazon Orders (required), choose an option in the drop-down:ĭisabled: Choose when you do not want to create corresponding orders in Magento when new orders are received from Amazon. Sets the product status to Disabled and the inventory setting to Do Not Manage Inventory creates a Magento catalog product with the SKU When an order is received from Amazon, the extension is set to Create Magento Order, and the ordered item SKU cannot be matched to an existing Magento catalog product, the order synchronization process: Orders created in Amazon Sales Channel display and can be managed in the Orders tab in Amazon Sales Channel Home. Amazon Sales Channel creates a matching order that corresponds to the Amazon order. This status change triggers Amazon Sales Channel to import the order and create a corresponding order. Once Amazon verifies the order and payment method, Amazon changes the order’s status to Unshipped. Amazon assigns a Pending status to newly created orders. When an order is created on Amazon, it is not immediately imported into Amazon Sales Channel. Orders that existed in Amazon in any status other than Unshipped prior to your store’s integration will not import. Amazon orders are imported and create new orders when the Amazon sets the order status to Unshipped. Order Settings define how Amazon orders are imported into and processed in Magento.īeginning when you integrate Amazon Sales Channel with your Amazon Seller Central account during onboarding, Amazon orders import and create new orders in Amazon Sales Channel. In the I Want To… section, click Order Settings. You can access your order settings for an Active or Inactive store in the store’s dashboard. Your order settings are configured first during onboarding, but can be modified at any time. The Adobe Commerce Merchant Documentation for current releases is published on the Adobe Experience League. ![]() The information on this page is intended for Adobe Commerce 2.3 customers who are on an extended support contract. ![]() ![]() ![]() The next person clockwise must then sing the following line of the song. The person who was last now goes first, and the person who first now went last. If the other players call them by their real name, they have to take a drink. The player who pulls the block must choose a new name for themselves for the rest of the game. □ Suggested read: Avalanche Drinking Game: Rules and Guides 25. The youngest person in the group must take a drink. The oldest person in the group must take a drink. The player whose birthday is closest to the current date must take a drink. The person closest to the door must take a drink. The tallest person in the group must take a drink. The smallest person in the group must take a drink. The player who pulls the block gets to choose another player to take a drink with them. When this block is pulled, everyone must take a shot. The player who pulls the block must take a shot. The player who pulls the block must finish their drink. This can be anything from “What’s your biggest fear?” to “Who would you want to be stranded on a deserted island with?”. The player who pulls the block must answer a question truthfully. □ Suggested read: Kings Cup □ Card Drinking Game: Rules, Ideas & App 14. If somebody can’t think of an answer or repeats an answer, they have to drink! ![]() The next player then has to call another thing within that category, and so on. The player who pulls the block chooses a category (e.g., animals) and names an item within that category. Anyone else in the group who has done that thing has to drink. For example, “I’ve never been skydiving”. The player who pulls the block says something they’ve never done before. The dare can be anything from singing a song to doing a silly dance. The player who pulls the block must do a dare. For example, they could say that every time somebody drinks, they have to tell a joke. The player who pulls the block gets to make a rule for the game. The last player to notice and put their thumb on the table has to take a drink. This means they can put their thumb on the table at any point during the game. The player who pulls the block becomes the thumb master. When this block is pulled, everyone starts drinking and can’t stop until the player to their right stops. The player who pulls the block gets to choose any player to take a drink. The player who pulls the block must make the player to their right drink. ![]() The player who pulls the block must make the player to their left drink. When this block is pulled, all players must take a drink. The player who pulls the block must take three drinks. The player who pulls the block must take two drinks. The player who pulls the block must take a drink. Make the game your own by adding rules to the blocks! Don’t worry we’ve got you covered with some fun ideas: 1. The player who pulls the block must follow the instruction on the label.Īdd your spin to the game by making up your own rules! Be creative and have fun! Keep reading for fun Jenga label ideas! Jenga drinking game block ideas □ ![]() For example, there may be a rule that says “drink 1” or “make a rule”. These labels correspond to rules that must be followed when the block is pulled. The main difference between this drinking game and regular Jenga is that there are labels on the blocks. ![]() ![]() It ain't like Street Fighter, where you can rip off a sequence of fast punches or kicks with quick button taps. The virtual joystick took some getting used to, as did the timing of action moves. But I soon found myself frustrated with the controls. I was immediately enamoured with the visual style. They knocked my socks off with Vector years ago so I was happy to give Shadow Fight a try. This is another brilliant mobile game from the folks at Nekki. I think how y’all designed the encounter mechanic is pretty unfair. No chance you lose, you will never get the exclusive weapon, no retry after you walk away. And also you need to realize that you can’t fight these guys again. When this happened to me in act 6, she said that I can’t let anyone have a doubt in my identity, which made me feel like I was screwing up the entire storyline and made me feel guilty, even though I tried my best using all the gems I had to retry the battle. And every time you try to walk away after you lost, May will stop you telling not to, giving you a reason. If you upgraded your equipments frequently, you might win, but if you’re one of those people that save up their money to upgrade your weapon to the next level without repeating survival mode more than 10 times, you’re not in luck. There is an option where you can go to the shop and buy yourself a new weapon or armor to help you out, but every time I didn’t have any money to do anything so I don’t see much point in that. Typically impossible, insane if lucky, and it’s one of those “If you get hit more than 3-4 times, you’re dead but you have to hit me at least 40 times, and also, you still lose 1/5 of your health if you block” impossible. To start this off, the enemy is WAY too hard. ![]() The game is overall good, but the one complaint I have is the encounter mechanic where you reach a certain range of levels and somebody approaches and challenges you. ![]() I would wait for that to come out or play this game casually for practice because the controls will have the same basic concept. That being said, SF3 isn't too far off now and I don't think it is feasible to complete the game before it comes out. It does require a ton of grinding to complete the game, but although I did spend $7 on microtransactions in appreciation of Nekki and the game, it is certainly possible to complete without spending any money. It is very stable and will run smoothly and without bugs even on my 5S. In the 3+ years I had this game I never experienced any issues with the controls at all. Additionally, there are no issues with moves not activating as I saw in another review. The controls are designed so that you can avoid these attacks and take advantage of the opening they create to start a chain of your own. I can say from personal experience that this is not something that is broken or even something that puts you at a disadvantage. I've been reading the reviews of the game, and people are saying that the CPU spamming ranged attacks is making the game hard to play. I have maxed out gear and levels and have the tempest rage legendary enchantment and a medium enchantment on all of my gear. Shadow Fight 2 is by far my favorite mobile game of all time. Customize your fighter with epic swords, nunchacku, armor suits, magical powers, and more. Journey through six different worlds full of menacing demons in this action-packed, adrenaline-fueled combat RPG with an immersive, intriguing storyline. Enter the "Underworld" and fight with friends against fearsome bosses! Devastate your enemies with delightfully intuitive controls, thanks to an all-new fighting interface designed especially for touchscreens. Plunge into epic combat sequences, rendered in astonishingly lifelike detail by an all-new animation system. Do you have what it takes to kick, punch, jump, and slash your way to victory? There’s only one way to find out. ![]() This game lets you equip your character with countless lethal weapons and rare armor sets, and features dozens of lifelike-animated Martial Arts techniques! Crush your enemies, humiliate demon bosses, and be the one to close the Gate of Shadows. The sequel to the famous Facebook smash hit with 40 million users!įrom the creators of Vector: Shadow Fight 2 is a nail-biting mix of RPG and classical Fighting. Epic battles in the Underworld are waiting! Unite with friends and fight! ![]() ![]() NO, a flashing car battery light does not indicate that there is a problem only with the battery. Can a blinking car battery light mean problems only with the battery? So, if you notice that the car battery light is flashing, you should take your car to a trusted mechanic to identify and fix the problem. Remember that the battery plays a crucial role in starting the engine and also powers other electrical components in the car. It should concern you because if the battery is not charging, it will eventually die causing your car to stall. YES, you need to be concerned because the warning indicates that the battery is not getting enough power. ![]() Do you need to be concerned if the car battery light flashes? Fixing damaged cables will cost anywhere between $20 and $50. Loose battery cables can also cause corrosion to set in at the terminal, leading to poor connection. These cables usually carry substantial current, especially when starting the engine and if they are not in good shape, then they will not be able to power the car as well as charge the battery when the car is on. If the cables that connect the alternator, voltage regulator, and battery are damaged, then they will not transmit power as they should, resulting in a low battery. Replacing a faulty voltage regulator will you anywhere between $330 and $450. ![]() As a result, the voltage will start dropping and if it reaches a point where the battery does not get sufficient charge, the sensor will take note and alert you by blinking the car battery on the dashboard. ![]() When the voltage regulator is damaged, it will not be able to control voltage. It is usually fitted between the alternator and the car’s electrical equipment, which includes the battery. The voltage regulator plays a vital role in ensuring that voltage remains stable in your car. Damaged voltage regulatorĪnother reason why the car battery light is blinking is that the voltage regulator is damaged. If the alternator is damaged, then you will have no choice but to replace it with a brand new one, and this will cost anywhere between $500 and $1000. When the performance of the alternator drops to a certain level, the car battery light will start to flicker. If it is faulty or damaged, then the battery will automatically take over and that will make the battery light on the dashboard flash. The alternator plays a crucial role in powering the car electronics and also charges the battery when the engine starts running. One of the top reasons why the car battery light is flashing is because there is a problem with the alternator. Possible causes of a flashing car battery light A faulty alternator This means that the chances of stalling are high if the problem is not fixed quickly. If there is enough juice to start the engine, your car will start but it won’t last for long because the battery is not charging properly. That is why all cars are equipped with a built-in recharging system which includes the voltage regulator and the alternator which charges the battery and provides the much-needed power when the engine is running.Īll vehicles are heavily reliant on the battery and that is why there is a car battery light on the dashboard to warn you if there is a problem with the recharging system. If the battery is not charged, then it will eventually die. The car battery light is flashing because the car is not getting enough power from the battery to enable it to operate as it should.Īll vehicles are equipped with a 12V rechargeable battery that powers everything, including the ignition system, headlights, DVD system, engine control computer, and much more. If it remains on when the engine is started, or if it’s flashing then there are some problems that need to be closely inspected by a mechanic. ![]() The battery light is supposed to turn on, then turn off when the engine starts. If you have noticed that the battery warning light is on, when you turn the ignition key, and remains on even when the engine is running, then that is a clear indication that there is something either with the battery itself, the connection, or other components that works alongside the battery. Can a faulty ECU cause a car battery light to flash?įlashing battery light on the car’s dashboard can be caused by a failing alternator, poor connecting cables, a damaged voltage regulator, or a loose battery.Can I drive with a blinking car battery light?.Can a blinking car battery light mean problems only with the battery?.Do you need to be concerned if the car battery light flashes?.Possible causes of a flashing car battery light. ![]() ![]() ![]() With this tool, there is extra control for you with all your current extensions, ads-on, and plugin in centralizing place, and even the hidden extensions can be easily found. GeekUninstaller is one of the best programs available over the internet that allow its users to perform deep and fast scanning to remove all types of leftovers from the system. It is one of the best options that allow Windows users to keep their PC clean all the time. ![]() ![]() The best about it is its force removal system that automatically removes those leftovers that are normally left by the default uninstaller. Its five main features and areas are clean removal, force removal, ultra-fast, support for Native 圆4 systems, and portable. Being a portable uninstaller means there is no need to install any software in the system at all.Īll you need is to download the free version of GeekUninstaller, and after that, you are ready to use it for free. Its clean and forced removal system forced the system registry to expel all those files and data that are usually left over by the standard removal programs or the default removal program of the Windows operating systems. Overall, it performs a very quick, deep, and fast scanning to remove every type of leftover from the system of its users. Uninstall Tool is one of the best uninstallers that make it easy and simple for its users to get their computers’ performance faster than before. With the usage of this uninstaller, the users can remove all those unwanted programs that are slowing down the performance of the system or those programs that the users want to remove but unable to do so. What makes it a special one is that it completely remove the selected program from the system, even from the registry. Its simple user interface and ease of access are known to be one of the best, powerful, and effective programs to be used. With the usage of this program, you will get the benefits in the shape of complete removal of unwanted programs, real-time installation monitor system, and controlling applications that run at the system startup. ![]() ![]() These are offered to expand the functionality of the basic text editor. Much like an iPhone (or WordPress,) Atom has extras that you can install called packages. The smart autocompletion is one of my favorite features, and the multiple panes should make you feel right at home with several panes open to edit code between files. Atom text editorĪnother great thing about Atom is that it’s a cross-platform system, working on operating systems like Linux, OS X, and Windows. This way, your team can create everything from branches to stages in one interface. Furthermore, Atom has a GitHub package already included with the text editor. An experienced developer should have no problem working with Atom, since it offers clean collaboration tools, a sleek editor, and some great organization tools for keeping your projects in check.Īll of your projects can be shared and edited in real-time, helping out teams that are far away from each other or simply those teams that want a more dedicated workspace. ![]() Also, there’s a community of developers who contribute themes and plugins, much like WordPress or some other opensource tools. In fact, the creators of Atom state that they made it just for developers. With Atom, you gain access to an open source text editor with developers in mind. The cross-platform abilities are also nice for launching the same text editor on all machines. These developers will enjoy the shortcut functionality and the high level of customization. Sublime Text makes the most sense for heavy coders.
![]() This is why new mutations that alter how the spike functions are of particular concern – they may impact how we control the spread of SARS-CoV-2. Another way would be to make the spikes “stickier” for our cells. ![]() One way this could occur is through a mutation on a part of the spike protein that prevents protective antibodies from binding to it. But some may cause changes that give the new version of the virus a selective advantage by making it more transmissible or infectious. Most mutations will not be beneficial and either stop the spike protein from working or have no effect on its function. Encoded within the viral genome, the protein can mutate and changes its biochemical properties as the virus evolves. One of the most concerning features of the spike protein of SARS-CoV-2 is how it moves or changes over time during the evolution of the virus. The SARS-CoV-2 virus is changing over time. Production of the spike inside our cells then starts the process of protective antibody and T cell production. Given how crucial the spike protein is to the virus, many antiviral vaccines or drugs are targeted to viral glycoproteins.įor SARS-CoV-2, the vaccines produced by Pfizer/BioNTech and Moderna give instructions to our immune system to make our own version of the spike protein, which happens shortly following immunisation. The spike is also involved in other processes like assembly, structural stability and immune evasion. ![]() One of these functional units binds to a protein on the surface of our cells called ACE2, triggering uptake of the virus particle and eventually membrane fusion. There are estimated to be roughly 26 spike trimers per virus. The spike protein of SARS-CoV-2 is stuck on the roughly spherical viral particle, embedded within the envelope and projecting out into space, ready to cling on to unsuspecting cells. The spike protein is made up of different sections that perform different functions. The spike can be subdivided into distinct functional units, known as domains, which fulfil different biochemical functions of the protein, such as binding to the target cell, fusing with the membrane, and allowing the spike to sit on the viral envelope. Spike proteins like to stick together and three separate spike molecules bind to each other to form a functional “trimeric” unit. The spike protein is composed of a linear chain of 1,273 amino acids, neatly folded into a structure, which is studded with up to 23 sugar molecules. ![]() Ebola viruses have one, the influenza virus has two, and herpes simplex virus has five. The spike protein of coronaviruses is one such viral glycoprotein. In order to gain entry to the inside of the cell, enveloped viruses use proteins (or glycoproteins as they are frequently covered in slippery sugar molecules) to fuse their own membrane to that of cells’ and take over the cell. Like cellular life, coronaviruses themselves are surrounded by a fatty membrane known as an envelope. Pišlar A, Mitrović A, Sabotič J, Pečar Fonović U, Perišić Nanut M, Jakoš T, et al, PLoS Pathog 16(11), CC BY How SARS-CoV-2 gets into cells and reproduces. Viruses must traverse this barrier to gain access to the cell. Due to the biochemical nature of fats, the outer surface is highly negatively charged and repellent. One of the major defences cellular life has against invaders is its outer coating, which is composed of a fatty layer that holds in all the enzymes, proteins and DNA that make up a cell. Our cells have evolved to ward off such intrusions. Instead, they have to get inside cells in order to replicate, where they use the cell’s own biochemical machinery to build new virus particles and spread to other cells or individuals. In the world of parasites, many bacterial or fungal pathogens can survive on their own without a host cell to infect. But what exactly is the spike protein and why is it so important? The SARS-CoV-2 coronavirus molecule. The spike protein is also the basis of current COVID-19 vaccines, which seek to generate an immune response against it. The new mutations may alter the biochemistry of the spike and could affect how transmissible the virus is. ![]() The new variant carries several peculiar changes to the spike protein when compared to other closely related variants – and that’s one of the reasons why it’s more concerning than other, harmless changes to the virus we have observed before. The emergence of a new variant of coronavirus has sparked renewed interest in the part of the virus known as the spike protein. ![]() |
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